基本信息
| 标准名称： | 硬质泡沫塑料平均泡孔尺寸试验方法 |
| 英文名称： | Test method for average cell size of rigid cellular plastics |
| 中标分类： |
化工 >>
合成材料 >>
合成树脂、塑料基础标准与通用方法 |
| ICS分类： |
橡胶和塑料工业 >>
泡沫材料
|
| 发布部门： | 国家技术监督局 |
| 发布日期： | 1991-04-28 |
| 实施日期： | 1992-02-01 |
| 首发日期： | 1991-04-28 |
| 作废日期： | 1900-01-01 |
| 主管部门： | 中国轻工业联合会 |
| 归口单位： | 全国塑料制品标准化技术委员会 |
| 起草单位： | 武汉塑料研究所 |
| 出版日期： | 1900-01-01 |
| 页数： | 2页 |
适用范围
本标准规定了测定硬质泡沫塑料平均泡孔尺寸的试验方法。本标准适用于硬质泡沫塑料平均泡孔尺寸的测定。
前言
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目录
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引用标准
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所属分类： 化工 合成材料 合成树脂 塑料基础标准与通用方法 橡胶和塑料工业 泡沫材料
【英文标准名称】:StandardTestMethodforImmunologicalMeasurementofFourPrincipalAllergenicProteins(Hevb1,3,5and6.02)inNaturalRubberandItsProductsDerivedfromLatex
【原文标准名称】:天然橡胶及其胶乳衍生物中4种主要过敏蛋白质(Hevb1,3,5和6.02)免疫学测量的试验方法
【标准号】:ASTMD7427-2008e1
【标准状态】:现行
【国别】:美国
【发布日期】:2008
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:D11.40
【标准类型】:(TestMethod)
【标准水平】:()
【中文主题词】:过敏原
【英文主题词】:allergens;Heveabrasiliensis;IEMA;immunoenzymetricassay;naturalrubberlatex;proteins;Allergens;Naturalrubber(NR);Naturalrubber(NR)latex;Proteins
【摘要】:IgE-mediatedallergicreactionstoproteinallergensinnaturalrubberlatexderivedfromtheHeveabrasiliensistreeemergedinthe1990sasaconcernwithoccasionalallergicmanifestations.Symptomsencompassinghives,uriticaria,rhinitis,asthmaandanaphylaxishaveallbeenreportedinlatexallergicindividualsexposedtoproductsderivedfromnaturalrubberlatex.SincenosafelevelofHevealatexallergenexposureisknown,avoidanceistheprimarymodeoftreatinglatexallergy.Asaresultofinvestigationsconductedbymanyscientistsacrosstheworld,thirteenlatexallergenshavesofarbeenidentifiedandcategorizedbytheAllergenNomenclatureSub-CommitteeoftheInternationalUnionofImmunologicalSocieties(IUIS)asHevb1toHevb13(Table1)(seeSpecificationD1193).ReportedsensitizationratesfortheseallergenicHevbproteinsvaryamongthemanyreportsasaresultofdifferencesinthestudypopulations,IgEantibodyassaymethodsandthequalityoftheHevballergensusedascalibratorsandqualitycontrolreagentsintheanalysis.Moststudies,however,agreethatHevb1andHevb3areimportantallergensforindividuals(forexample,childrenwithspinabifida)whoareexposedthroughmucosalcontactasaresultofmultiplesurgeriesorlatexcatheteruseforanextendedperiodoftime.Additionally,investigatorsperformingsensitizationstudiesalsoagreethatHevb5andHevb6.02areimportantallergensthatmayelicitsensitizationingenetically-predisposedindividualswhoareexposedtonaturalrubberlatex(2-4).Onthebasisoftheseclinicalstudies,assaysforthesefourallergenicproteins(thatis,Hevb1,Hevb3,Hevb5andHevb6.02)havebeendevelopedandtheyarethusthesubjectofthisstandard.Adoptionofimmunoenzymetricassayreagentsandstandardproteinsneededtoquantifyotherlatexallergens(otherthanHevb1,3,5,and6.02)inextractsofnaturalrubberlatexproductswillrequireseparatedocumentationandvalidation.1.1Thistestmethodcoversanimmunologicalmethodknownasanimmunoenzymetricassaytoquantifytheamountof4principalHeveabrasiliensis[Hevb]allergenicproteins[Hevb1,Hevb3,Hevb5andHevb6.02]innaturalrubberanditsproductsderivedfromlatexusingmonoclonalantibodiesspecificforepitopesontheseproteins.Sincetheseassaysquantifythelevelsofonly4oftheknown13officiallyacknowledgedallergenspotentiallypresentinnaturalrubberlatexcontainingproducts,thesumofthefourallergenlevelsshallbeviewedasanindicatoroftheallergenburdenandnotasameasureofthetotalallergencontentthatcanbereleasedfromtheproduct.1.2Forthepurposeofthistestmethod,therangeofallergenicproteinwillbemeasuredintermsofnanogramtomicrogramquantitiespergramorunitsurfaceareaofanaturalrubbercontainingproduct.1.3ThetestmethodisnotdesignedtoevaluatethepotentialofnaturalrubbercontainingmaterialstoinduceorelicitTypeI(IgE-mediated)hypersensitivityreactions.1.4Thistestmethodshouldbeusedundercontrolledlaboratoryconditionstodetectandquantifythelevelof4allergenicproteinsfoundinnaturalrubbercontainingproducts.Itshouldnotbeusedtodescribe,appraiseorassessthehazardorriskofthesenaturalrubbercontainingmaterialsorproductsunderactualinuseconditions.1.5ThevaluesstatedinSIunitsaretoberegardedasstandard.Nootherunitsofmeasurementareincludedinthisstandard.1.6Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Iti......
【中国标准分类号】:B72
【国际标准分类号】:83_060
【页数】:16P.;A4
【正文语种】:英语